Title : Association of Vitamin D Pathway Genetic Variation and Thyroid Cancer.

Pub. Date : 2019 Jul 28

PMID : 31357732






3 Functional Relationships(s)
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1 Genetic variants close to genes that encode crucial enzymes for the synthesis (DHCR7 rs12785878), metabolism (CYP2R1 rs2060793) and degradation (CYP24A1 rs6013897) of vitamin D have been associated with serum levels of vitamin D. Vitamin D 7-dehydrocholesterol reductase Homo sapiens
2 Genetic variants close to genes that encode crucial enzymes for the synthesis (DHCR7 rs12785878), metabolism (CYP2R1 rs2060793) and degradation (CYP24A1 rs6013897) of vitamin D have been associated with serum levels of vitamin D. Vitamin D 7-dehydrocholesterol reductase Homo sapiens
3 These findings suggest that DHCR7 polymorphisms may be associated with an increased risk of thyroid cancer due to an effect of this gene on circulating vitamin D levels. Vitamin D 7-dehydrocholesterol reductase Homo sapiens