Title : In vitro evidence for the involvement of at least two forms of human liver UDP-glucuronosyltransferase in morphine 3-glucuronidation.

Pub. Date : 1988 Jul 15

PMID : 3134892






1 Functional Relationships(s)
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1 Chloramphenicol, 4-hydroxybiphenyl, 4-methylumbelliferone, 1-naphthol and 4-nitrophenol were all shown to inhibit the low affinity morphine-UDPGT activity, but only chloramphenicol and 1-naphthol were competitive inhibitors. 4-nitrophenol UDP glucuronosyltransferase family 1 member A4 Homo sapiens