Pub. Date : 2019
PMID : 31339834
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PURPOSE: Hydroxylation activity at the 6beta-position of steroid hormones (testosterone, progesterone, and cortisol) by human cytochromes P450 (P450 or CYP) 3A4 and CYP3A5 and their molecular docking energy values were compared to understand the catalytic properties of the major forms of human CYP3A, namely, CYP3A4 and CYP3A5. | Hydrocortisone | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | PURPOSE: Hydroxylation activity at the 6beta-position of steroid hormones (testosterone, progesterone, and cortisol) by human cytochromes P450 (P450 or CYP) 3A4 and CYP3A5 and their molecular docking energy values were compared to understand the catalytic properties of the major forms of human CYP3A, namely, CYP3A4 and CYP3A5. | Hydrocortisone | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 3 | METHODS: Testosterone, progesterone, and cortisol 6beta-hydroxylation activities of recombinant CYP3A4 and CYP3A5 were determined by liquid chromatography. | Hydrocortisone | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |