Pub. Date : 2019 Aug 29
PMID : 31339677
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | BACKGROUND: Two drugs under consideration for inclusion in antiretroviral therapy (ART) regimens for human immunodeficiency virus (HIV) infection are dolutegravir (DTG) and tenofovir alafenamide fumarate (TAF). | dolutegravir | TATA-box binding protein associated factor 8 | Homo sapiens |
2 | BACKGROUND: Two drugs under consideration for inclusion in antiretroviral therapy (ART) regimens for human immunodeficiency virus (HIV) infection are dolutegravir (DTG) and tenofovir alafenamide fumarate (TAF). | dolutegravir | TATA-box binding protein associated factor 8 | Homo sapiens |
3 | CONCLUSIONS: Treatment with DTG combined with either of two tenofovir prodrugs (TAF and TDF) showed noninferior efficacy to treatment with the standard-care regimen. | dolutegravir | TATA-box binding protein associated factor 8 | Homo sapiens |
4 | There was significantly more weight gain with the DTG-containing regimens, especially in combination with TAF, than with the standard-care regimen. | dolutegravir | TATA-box binding protein associated factor 8 | Homo sapiens |