Title : IL-4/B cell stimulatory factor 1 stimulates T cell growth by an IL-2-independent mechanism.

Pub. Date : 1988 Jul 15

PMID : 3133410






1 Functional Relationships(s)
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1 This response of T cells to IL-4 plus PMA is independent of the action of IL-2 as judged by 1) the lack of IL-2 in supernatants of stimulated cells, 2) the failure to detect IL-2 mRNA in stimulated cells by in situ hybridization, 3) the inability of anti-IL-2R antibody and of anti-IL-2 antibody to block responses to IL-4 plus PMA, and 4) the failure of cyclosporin A to block responses. Cyclosporine interleukin 4 Mus musculus