Title : Cepharanthine hydrochloride degrades polyglutamine-expanded androgen receptor proteins through an autophagy pathway in neuron cells.

Pub. Date : 2019 Oct 15

PMID : 31310754






1 Functional Relationships(s)
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1 Spinal and bulbar muscular atrophy (SBMA) is a late-onset neurodegenerative neuromuscular disease without effective therapy, and the protein toxicity of androgen-dependent polyglutamine-expanded androgen receptor is thought to contribute to its etiology. polyglutamine androgen receptor Homo sapiens