Pub. Date : 1988 Jun 15
PMID : 3130982
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In response to phorbol esters such as 12-O-tetradecanoylphorbol-13-acetate (TPA), HL-60 cells differentiate to macrophage-like cells and exhibit the ability to phosphorylate vinculin in vitro. | Tetradecanoylphorbol Acetate | vinculin | Homo sapiens |
| 2 | In response to phorbol esters such as 12-O-tetradecanoylphorbol-13-acetate (TPA), HL-60 cells differentiate to macrophage-like cells and exhibit the ability to phosphorylate vinculin in vitro. | Tetradecanoylphorbol Acetate | vinculin | Homo sapiens |
| 3 | Coincident with these changes after TPA treatment was a reduction in Ca2+ and phospholipid-independent phosphorylation of vinculin in vitro in extracts from HL-60/ADR cells, whereas HL-60 cells exhibited an elevation of this phosphoprotein. | Tetradecanoylphorbol Acetate | vinculin | Homo sapiens |
| 4 | The phosphorylation of vinculin in TPA-treated HL-60 cells or untreated HL-60/ADR cells was blocked by antibodies to protein kinase C. | Tetradecanoylphorbol Acetate | vinculin | Homo sapiens |