Title : Nicotinamide Augments the Anti-Inflammatory Properties of Resveratrol through PARP1 Activation.

Pub. Date : 2019 Jul 15

PMID : 31308445






3 Functional Relationships(s)
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1 Nicotinamide Augments the Anti-Inflammatory Properties of Resveratrol through PARP1 Activation. Niacinamide poly(ADP-ribose) polymerase 1 Homo sapiens
2 Consistently, treatment with PARP1 inhibitor antagonized the anti-inflammatory effect of both RSV and NAM. Niacinamide poly(ADP-ribose) polymerase 1 Homo sapiens
3 For the first time, we report the ability of NAM to augment PARP1 activation, induced by RSV, and its associated anti-inflammatory effects mediated through the induction of BCL6 with the concomitant down regulation of COX-2. Niacinamide poly(ADP-ribose) polymerase 1 Homo sapiens