Title : Angiotensin II mediates the axonal trafficking of tyrosine hydroxylase and dopamine β-hydroxylase mRNAs and enhances norepinephrine synthesis in primary sympathetic neurons.

Pub. Date : 2019 Sep

PMID : 31306490






1 Functional Relationships(s)
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1 Taken together, our results point to a novel mechanism by which Ang II participates in the regulation of axonal synthesis of NE by modulating the local trafficking and expression of TH and DBH, two key enzymes involved in the catecholamine biosynthetic pathway. Catecholamines angiotensinogen Rattus norvegicus