Title : Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease.

Pub. Date : 2019 Oct 15

PMID : 31301562






1 Functional Relationships(s)
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1 Acting as an open-channel blocker, the anti-AD drug memantine preferentially targets NMDAR overactivation, which has been proposed to trigger neurotoxic events mediated by amyloid beta peptide (Abeta) and oxidative stress. Memantine amyloid beta precursor protein Homo sapiens