Title : Quality Control in Huntington's Disease: a Therapeutic Target.

Pub. Date : 2019 Oct

PMID : 31297710






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 In HD, abnormal expansion of glutamine repeats in the protein huntingtin leads to toxic aggregation of huntingtin which in turn impairs the quality control mechanism of cells through damaging the machineries involved in removal of aggregated abnormal protein. Glutamine huntingtin Homo sapiens
2 In HD, abnormal expansion of glutamine repeats in the protein huntingtin leads to toxic aggregation of huntingtin which in turn impairs the quality control mechanism of cells through damaging the machineries involved in removal of aggregated abnormal protein. Glutamine huntingtin Homo sapiens