Pub. Date : 2019 Jul 1
PMID : 31288895
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These results revealed that flucloxacillin might have weak pharmacokinetic interactions on midazolam metabolized into 1"-hydroxy midazolam, indicating that there was weak induction to CYP3A by flucloxacillin and that there was at least 30.80 % of metabolic behaviour in change with bioavailability decreased by 38.11 % that took effect to flucloxacillin metabolism for liver injury in CPY3A4 poor metabolic polymorphisms. | Floxacillin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | These results revealed that flucloxacillin might have weak pharmacokinetic interactions on midazolam metabolized into 1"-hydroxy midazolam, indicating that there was weak induction to CYP3A by flucloxacillin and that there was at least 30.80 % of metabolic behaviour in change with bioavailability decreased by 38.11 % that took effect to flucloxacillin metabolism for liver injury in CPY3A4 poor metabolic polymorphisms. | Floxacillin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 3 | These results revealed that flucloxacillin might have weak pharmacokinetic interactions on midazolam metabolized into 1"-hydroxy midazolam, indicating that there was weak induction to CYP3A by flucloxacillin and that there was at least 30.80 % of metabolic behaviour in change with bioavailability decreased by 38.11 % that took effect to flucloxacillin metabolism for liver injury in CPY3A4 poor metabolic polymorphisms. | Floxacillin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |