Title : The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.

Pub. Date : 2019 Jul 6

PMID : 31284572






1 Functional Relationships(s)
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1 The NLRP3 inflammasome is activated by diverse stimuli, and multiple molecular and cellular events, including ionic flux, mitochondrial dysfunction, and the production of reactive oxygen species, and lysosomal damage have been shown to trigger its activation. Oxygen NLR family pyrin domain containing 3 Homo sapiens