Title : Epidermal papillomas and carcinomas induced in uninitiated mouse skin by tumor promoters alone contain a point mutation in the 61st codon of the Ha-ras oncogene.

Pub. Date : 1988 Apr

PMID : 3128410






1 Functional Relationships(s)
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1 Previous results in a number of laboratories have demonstrated that epidermal papillomas and carcinomas induced by the two-stage protocol of initiation and promotion contain a point mutation in the 61st codon of the c-Ha-ras oncogene when the initiating agent used is 7,12-dimethylbenz[a]anthracene (DMBA). 9,10-Dimethyl-1,2-benzanthracene Harvey rat sarcoma virus oncogene Mus musculus