Pub. Date : 2019 Oct
PMID : 31276230
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Calycosin induces apoptosis in adenocarcinoma HT29 cells by inducing cytotoxic autophagy mediated by SIRT1/AMPK-induced inhibition of Akt/mTOR. | 7,3'-dihydroxy-4'-methoxyisoflavone | AKT serine/threonine kinase 1 | Homo sapiens |
2 | In conclusion, Calycosin stimulates CRC cell apoptosis and inhibits their invasion by acting as SIRT1 activator which induces activation of AMPK-induced inhibition of Akt/mTOR axis. | 7,3'-dihydroxy-4'-methoxyisoflavone | AKT serine/threonine kinase 1 | Homo sapiens |