Pub. Date : 2019 Jul 15
PMID : 31270147
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment of 16HBE cells and Balb/c mice with ergosterol inhibited CSE-induced inflammatory and oxidative stress and apoptosis by inhibiting the activation of NF-kappaB/p65. | Ergosterol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 2 | Ergosterol suppressed apoptosis by inhibiting the expression of the apoptosis-related proteins both in vitro and in vivo Moreover, the usage of QNZ (an inhibitor of NF-kappaB) also partly demonstrated that NF-kappaB/p65 pathway was involved in the ergosterol protective progress. | Ergosterol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 3 | Ergosterol suppressed apoptosis by inhibiting the expression of the apoptosis-related proteins both in vitro and in vivo Moreover, the usage of QNZ (an inhibitor of NF-kappaB) also partly demonstrated that NF-kappaB/p65 pathway was involved in the ergosterol protective progress. | Ergosterol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 4 | Ergosterol suppressed apoptosis by inhibiting the expression of the apoptosis-related proteins both in vitro and in vivo Moreover, the usage of QNZ (an inhibitor of NF-kappaB) also partly demonstrated that NF-kappaB/p65 pathway was involved in the ergosterol protective progress. | Ergosterol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 5 | Ergosterol suppressed apoptosis by inhibiting the expression of the apoptosis-related proteins both in vitro and in vivo Moreover, the usage of QNZ (an inhibitor of NF-kappaB) also partly demonstrated that NF-kappaB/p65 pathway was involved in the ergosterol protective progress. | Ergosterol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 6 | These results show that ergosterol suppressed COPD inflammatory and oxidative stress and apoptosis through the NF-kappaB/p65 pathway, suggesting that ergosterol may be partially responsible for the therapeutic effects of cultured C. sinensis on COPD patients. | Ergosterol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 7 | These results show that ergosterol suppressed COPD inflammatory and oxidative stress and apoptosis through the NF-kappaB/p65 pathway, suggesting that ergosterol may be partially responsible for the therapeutic effects of cultured C. sinensis on COPD patients. | Ergosterol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |