Title : Reductive methylation of lysine residues in acidic fibroblast growth factor: effect on mitogenic activity and heparin affinity.

Pub. Date : 1988 Jan 26

PMID : 3126814






1 Functional Relationships(s)
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1 Reductive methylation of bovine brain derived acidic fibroblast growth factor (aFGF) with formaldehyde and sodium cyanoborohydride reduces its capacity to stimulate mitogenesis in Balb/C 3T3 cells, and this correlates with the modification of less than 3 of its 12 lysine residues. sodium cyanoborohydride fibroblast growth factor 1 Bos taurus