Title : Nrf2 drives oxidative stress-induced autophagy in nucleus pulposus cells via a Keap1/Nrf2/p62 feedback loop to protect intervertebral disc from degeneration.

Pub. Date : 2019 Jul 1

PMID : 31263165






1 Functional Relationships(s)
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1 The detrimental effects of H2O2-induced oxidative stress were increased in autophagy-deficient cells via reduced expression of Atg7 and the Keap1-Nrf2-p62 autophagy pathway. Hydrogen Peroxide nuclear factor, erythroid derived 2, like 2 Mus musculus