Title : Effects of sex steroids on growth hormone responses to clonidine and GHRH in reserpine pretreated rats.

Pub. Date : 1988

PMID : 3126262






4 Functional Relationships(s)
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1 Administration of reserpine in a dose causing depletion of brain monoamines led to a complete suppression of the pulsatile secretory pattern of growth hormone (GH) in gonadectomized (GX) as well as in sham-operated male and female rats. Reserpine gonadotropin releasing hormone receptor Rattus norvegicus
2 Administration of reserpine in a dose causing depletion of brain monoamines led to a complete suppression of the pulsatile secretory pattern of growth hormone (GH) in gonadectomized (GX) as well as in sham-operated male and female rats. Reserpine gonadotropin releasing hormone receptor Rattus norvegicus
3 In GX animals of both sexes treated with estradiol, but not in those treated with testosterone or dihydrotestosterone (DHT), the reserpine induced inhibition of GH release was partially antagonized. Reserpine gonadotropin releasing hormone receptor Rattus norvegicus
4 Administration of the alpha 2-adrenoceptor agonist clonidine caused secretion of GH in reserpine pretreated, sham-operated rats. Reserpine gonadotropin releasing hormone receptor Rattus norvegicus