Title : Progesterone promotes embryo adhesion by upregulating c-Fos/c-Jun transcription factor-mediated poFUT1 expression†.

Pub. Date : 2019 Oct 25

PMID : 31260062






2 Functional Relationships(s)
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1 Employing a human embryo trophoblastic cell line (JAR), we showed that progesterone facilitated the activation of c-Fos/c-Jun. Progesterone Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 Taking these findings together, progesterone upregulates poFUT1 expression via the specific transcription factor c-Fos/c-Jun, and then increase trophoblast cell proliferation and adhesion potential. Progesterone Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens