Title : IPH4102, a first-in-class anti-KIR3DL2 monoclonal antibody, in patients with relapsed or refractory cutaneous T-cell lymphoma: an international, first-in-human, open-label, phase 1 trial.

Pub. Date : 2019 Aug

PMID : 31253572






2 Functional Relationships(s)
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1 IPH4102, a first-in-class anti-KIR3DL2 monoclonal antibody, in patients with relapsed or refractory cutaneous T-cell lymphoma: an international, first-in-human, open-label, phase 1 trial. iph4102 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 Homo sapiens
2 BACKGROUND: IPH4102 is a first-in-class monoclonal antibody targeting KIR3DL2, a cell surface protein that is expressed in cutaneous T-cell lymphoma, and predominantly in its leukaemic form, Sezary syndrome. iph4102 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 Homo sapiens