Title : Mechanistic Insights into the Metal-Dependent Activation of ZnII-Dependent Metallochaperones.

Pub. Date : 2019 Oct 21

PMID : 31247880






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CoII titrations reveal that both metallochaperones have similar electronic absorption characteristics that indicate the presence of two tetrahedral metal coordination sites. Metals mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 High-affinity metal binding at the CXCC motif activates the GTPase activity of both enzymes, with ZnII more effective than CoII. Metals mitochondrially encoded cytochrome c oxidase II Homo sapiens