Pub. Date : 2019 Jul 11
PMID : 31244108
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A proline-centered pentapeptide isoconformational to arachidonic acid, which exhibited appreciable selectivity for COX-2, overcoming acetic acid- and formalin-induced pain in rats to almost 80%, was treated as a substrate by the enzyme. | Arachidonic Acid | cytochrome c oxidase II, mitochondrial | Rattus norvegicus |
| 2 | The kinetic parameter Kcat/Km for COX-2-mediated metabolism of the peptide (6.3 x 105 M-1 s-1) was quite similar to 9.5 x 105 M-1 s-1 for arachidonic acid. | Arachidonic Acid | cytochrome c oxidase II, mitochondrial | Rattus norvegicus |