Title : Unraveling Sugar Binding Modes to DC-SIGN by Employing Fluorinated Carbohydrates.

Pub. Date : 2019 Jun 25

PMID : 31242623






1 Functional Relationships(s)
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1 A fluorine nuclear magnetic resonance (19F-NMR)-based method is employed to assess the binding preferences and interaction details of a library of synthetic fluorinated monosaccharides towards dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN), a lectin of biomedical interest, which is involved in different viral infections, including HIV and Ebola, and is able to recognize a variety of self- and non-self-glycans. Polysaccharides CD209 molecule Homo sapiens