Title : Design, Synthesis, and Evaluation of Isoquinoline Ureas as TRPV1 Antagonists.

Pub. Date : 2020

PMID : 31241438






1 Functional Relationships(s)
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1 Another heteroaryl urea derivative, A-425619 1, has been reported to be a potent and selective TRPV1 antagonist of capsaicin-evoked receptor activation with an IC50 value of 4 nM in hTRPV1. Capsaicin transient receptor potential cation channel subfamily V member 1 Cavia porcellus