Title : Low-dose bradykinin infusion reduces endogenous glucose production in surgical patients.

Pub. Date : 1988 Feb

PMID : 3123876






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1 Low-dose bradykinin infusion reduces endogenous glucose production in surgical patients. Glucose kininogen 1 Homo sapiens
2 The systemic effect of low-dose bradykinin infusion on total body glucose production and arterial substrate concentrations was examined during D5W infusion (1.0 mg/kg/min) in five normal-weight postsurgical subjects and compared to the response in four saline infused control patients, well matched for age, weight, and degree of postoperative stress. Glucose kininogen 1 Homo sapiens
3 The systemic effect of low-dose bradykinin infusion on total body glucose production and arterial substrate concentrations was examined during D5W infusion (1.0 mg/kg/min) in five normal-weight postsurgical subjects and compared to the response in four saline infused control patients, well matched for age, weight, and degree of postoperative stress. Glucose kininogen 1 Homo sapiens
4 After 75 minutes of bradykinin, endogenous glucose production was significantly reduced as compared to basal values (1.63 +/- 0.21 mg/kg/min, P less than .0125 v 2.20 +/- 0.35 basal). Glucose kininogen 1 Homo sapiens
5 These results demonstrate the inhibitory effect of low-dose bradykinin on glucose production in surgically stressed patients. Glucose kininogen 1 Homo sapiens