Title : SARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes.

Pub. Date : 2019

PMID : 31231549






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mechanistically, ORF8b interacts directly with the Leucine Rich Repeat domain of NLRP3 and localizes with NLRP3 and ASC in cytosolic dot-like structures. Leucine NLR family pyrin domain containing 3 Homo sapiens