Title : Quercetin Inhibits the Production of IL-1β-Induced Inflammatory Cytokines and Chemokines in ARPE-19 Cells via the MAPK and NF-κB Signaling Pathways.

Pub. Date : 2019 Jun 17

PMID : 31212975






2 Functional Relationships(s)
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1 The results showed that quercetin could dose-dependently decrease the mRNA and protein levels of ICAM-1, IL-6, IL-8 and monocyte chemoattractant protein-1 (MCP-1). Quercetin interleukin 6 Homo sapiens
2 Taken together, these results provide evidence that quercetin protects ARPE-19 cells from the IL-1beta-stimulated increase in ICAM-1, sICAM-1, IL-6, IL-8 and MCP-1 production by blocking the activation of MAPK and NF-kappaB signaling pathways to ameliorate the inflammatory response. Quercetin interleukin 6 Homo sapiens