Title : Platelet-derived growth factor-induced alterations in vinculin distribution in porcine vascular smooth muscle cells.

Pub. Date : 1987

PMID : 3121190






3 Functional Relationships(s)
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1 Disappearance of vinculin staining from adhesion plaques is also caused by 12-O-tetradecanoyl-phorbol-13-acetate (TPA; 200-400 nM), though the time course of the disappearance of vinculin staining under these conditions takes longer than in cells exposed to PDGF. Tetradecanoylphorbol Acetate vinculin Homo sapiens
2 Disappearance of vinculin staining from adhesion plaques is also caused by 12-O-tetradecanoyl-phorbol-13-acetate (TPA; 200-400 nM), though the time course of the disappearance of vinculin staining under these conditions takes longer than in cells exposed to PDGF. Tetradecanoylphorbol Acetate vinculin Homo sapiens
3 Both PDGF (20 ng/ml) and TPA (100 nM) caused cytosolic alkalinization which occurred after PDGF-induced disruption of vinculin from adhesion plaques, as determined using the pH-sensitive indicator BCECF and Digitized Video Microscopy. Tetradecanoylphorbol Acetate vinculin Homo sapiens