Title : Inhibition of NLRP3 inflammasome-mediated pyroptosis in macrophage by cycloastragenol contributes to amelioration of imiquimod-induced psoriasis-like skin inflammation in mice.

Pub. Date : 2019 Sep

PMID : 31203155






2 Functional Relationships(s)
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1 Inhibition of NLRP3 inflammasome-mediated pyroptosis in macrophage by cycloastragenol contributes to amelioration of imiquimod-induced psoriasis-like skin inflammation in mice. Imiquimod NLR family, pyrin domain containing 3 Mus musculus
2 Taken together, the results show that CAG selectively modulates macrophage function by inhibiting NLRP3 inflammasome-mediated pyroptosis to ameliorate IMQ-induced psoriasis-like skin inflammation in mice. Imiquimod NLR family, pyrin domain containing 3 Mus musculus