Title : Cannabidiol Overcomes Oxaliplatin Resistance by Enhancing NOS3- and SOD2-Induced Autophagy in Human Colorectal Cancer Cells.

Pub. Date : 2019 Jun 5

PMID : 31195721






1 Functional Relationships(s)
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1 The combination of oxaliplatin and CBD decreased NOS3 phosphorylation, which resulted in autophagy, by inducing the overproduction of ROS through mitochondrial dysfunction, thus overcoming oxaliplatin resistance. Reactive Oxygen Species nitric oxide synthase 3 Homo sapiens