Pub. Date : 2019
PMID : 31182989
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cyclophilin A (CyPA) is a major ROS-induced factor in atherosclerosis. | Reactive Oxygen Species | peptidylprolyl isomerase A | Homo sapiens |
| 2 | Cyclophilin A (CyPA) is a major ROS-induced factor in atherosclerosis. | Reactive Oxygen Species | peptidylprolyl isomerase A | Homo sapiens |
| 3 | There is a positive feedback mechanism between CyPA and ROS, which enables the oxidative stress response to continue and expand. | Reactive Oxygen Species | peptidylprolyl isomerase A | Homo sapiens |
| 4 | By dihydroethidium (DHE) staining and electron spin resonance (ESR) assays, we demonstrated that CyPA reduced ROS production and suppressed O2 - production dependent on reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. | Reactive Oxygen Species | peptidylprolyl isomerase A | Homo sapiens |