Title : Colchicine Myopathy: A Case Series Including Muscle MRI and ABCB1 Polymorphism Data.

Pub. Date : 2019

PMID : 31178824






4 Functional Relationships(s)
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1 Colchicine Myopathy: A Case Series Including Muscle MRI and ABCB1 Polymorphism Data. Colchicine ATP binding cassette subfamily B member 1 Homo sapiens
2 ABCB1 is important to the metabolism of colchicine, so we speculated that it was possible that colchicine myopathy patients may have a particular genotype that is associated with this side effect. Colchicine ATP binding cassette subfamily B member 1 Homo sapiens
3 ABCB1 is important to the metabolism of colchicine, so we speculated that it was possible that colchicine myopathy patients may have a particular genotype that is associated with this side effect. Colchicine ATP binding cassette subfamily B member 1 Homo sapiens
4 We additionally present an analysis of four genetic polymorphisms in ABCB1 and transcript levels in muscle tissue, and demonstrate the descriptive finding of reduced ABCB1 transcript levels in the colchicine myopathy patients. Colchicine ATP binding cassette subfamily B member 1 Homo sapiens