Title : Enhancing effect of taurohyodeoxycholate on ABCB4-mediated phospholipid efflux.

Pub. Date : 2019 Oct

PMID : 31176036






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In this study, we assessed the effects of taurine- or glycine-conjugated cholate, ursodeoxycholate and hyodeoxycholate on the ABCB4-mediated phosphatidylcholine (PC) efflux using Abcb4 knockout mice and HEK293 cells stably expressing ABCB4. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens
2 In this study, we assessed the effects of taurine- or glycine-conjugated cholate, ursodeoxycholate and hyodeoxycholate on the ABCB4-mediated phosphatidylcholine (PC) efflux using Abcb4 knockout mice and HEK293 cells stably expressing ABCB4. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens
3 We also showed that the PC efflux from ABCB4-expressing HEK293 cells was stimulated by taurohyodeoxycholate much more strongly than the other tested bile salts. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens
4 Therefore, the enhancing effect of taurohyodeoxycholate on the ABCB4-mediated PC efflux may be due to the strong mixed micelle formation ability. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens