Title : Discovery of natural pentacyclic triterpenoids as potent and selective inhibitors against human carboxylesterase 1.

Pub. Date : 2019 Sep

PMID : 31175950






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Human carboxylesterase 1 (CES1), primarily expressed in the liver and adipocytes, is responsible for the hydrolysis of endogenous esters (such as cholesteryl esters and triacylglycerols) and the metabolism of xenobiotic esters (such as clopidogrel and oseltamivir), thus participates in physiological and pathological processes. Oseltamivir carboxylesterase 1 Homo sapiens
2 Human carboxylesterase 1 (CES1), primarily expressed in the liver and adipocytes, is responsible for the hydrolysis of endogenous esters (such as cholesteryl esters and triacylglycerols) and the metabolism of xenobiotic esters (such as clopidogrel and oseltamivir), thus participates in physiological and pathological processes. Oseltamivir carboxylesterase 1 Homo sapiens