Pub. Date : 2019
PMID : 31168030
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The anti-cancer drug gefitinib accelerates Fas-mediated apoptosis by enhancing caspase-8 activation in cancer cells. | ammonium ferrous sulfate | caspase 8 | Homo sapiens |
| 2 | In the presence of nontoxic concentrations of gefitinib, Fas-induced activation of caspase-8 and subsequent apoptosis was dramatically promoted, suggesting that gefitinib increases the sensitivity to Fas-mediated apoptosis. | ammonium ferrous sulfate | caspase 8 | Homo sapiens |
| 3 | In the presence of nontoxic concentrations of gefitinib, Fas-induced activation of caspase-8 and subsequent apoptosis was dramatically promoted, suggesting that gefitinib increases the sensitivity to Fas-mediated apoptosis. | ammonium ferrous sulfate | caspase 8 | Homo sapiens |