Title : The anti-cancer drug gefitinib accelerates Fas-mediated apoptosis by enhancing caspase-8 activation in cancer cells.

Pub. Date : 2019

PMID : 31168030






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The anti-cancer drug gefitinib accelerates Fas-mediated apoptosis by enhancing caspase-8 activation in cancer cells. ammonium ferrous sulfate caspase 8 Homo sapiens
2 In the presence of nontoxic concentrations of gefitinib, Fas-induced activation of caspase-8 and subsequent apoptosis was dramatically promoted, suggesting that gefitinib increases the sensitivity to Fas-mediated apoptosis. ammonium ferrous sulfate caspase 8 Homo sapiens
3 In the presence of nontoxic concentrations of gefitinib, Fas-induced activation of caspase-8 and subsequent apoptosis was dramatically promoted, suggesting that gefitinib increases the sensitivity to Fas-mediated apoptosis. ammonium ferrous sulfate caspase 8 Homo sapiens