Title : Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease.

Pub. Date : 2019 Aug 2

PMID : 31154939






2 Functional Relationships(s)
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1 Metformin treatment decreased inflammation, IL-6 levels, STAT3 activation, and human PA smooth muscle cell proliferation. Metformin interleukin 6 Homo sapiens
2 In vivo, in the supracoronary aortic banding+MetS animals, reducing IL-6, either by anti-IL-6 antibody or metformin treatment, reversed pulmonary vascular remodeling and improve PH due to LHD. Metformin interleukin 6 Homo sapiens