Title : Local inflammation alters the lung disposition of a drug loaded pegylated liposome after pulmonary dosing to rats.

Pub. Date : 2019 Aug 10

PMID : 31152749






1 Functional Relationships(s)
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1 Concentrations of the pro-inflammatory cytokine IL-1beta were increased in bronchoalveolar lavage fluid after a single pulmonary dose of liposomes to rats with inflamed lungs, but no other significant changes in lung inflammatory markers were identified in healthy or bleomycin-challenged rats. Bleomycin interleukin 1 alpha Rattus norvegicus