Pub. Date : 2019 Aug 25
PMID : 31150632
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Transcriptomic analyses reveal the molecular mechanisms of schisandrin B alleviates CCl4-induced liver fibrosis in rats by RNA-sequencing. | schizandrin B | C-C motif chemokine ligand 4 | Rattus norvegicus |
2 | This study aimed to investigate the therapeutic effects and molecular mechanisms of Sch B against CCl4-induced liver fibrosis in rats. | schizandrin B | C-C motif chemokine ligand 4 | Rattus norvegicus |
3 | The results demonstrated that Sch B effectively alleviated CCl4-induced liver damage and fibrosis in rats, as evidenced by improved liver function and decreased extracellular matrix deposition. | schizandrin B | C-C motif chemokine ligand 4 | Rattus norvegicus |
4 | In conclusion, our study demonstrated Sch B alleviated CCl4-induced liver fibrosis by multiple modulatory mechanisms, which provide new clues for further pharmacological study of Sch B. | schizandrin B | C-C motif chemokine ligand 4 | Rattus norvegicus |