Title : Transcriptomic analyses reveal the molecular mechanisms of schisandrin B alleviates CCl4-induced liver fibrosis in rats by RNA-sequencing.

Pub. Date : 2019 Aug 25

PMID : 31150632






4 Functional Relationships(s)
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Protein Name
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1 Transcriptomic analyses reveal the molecular mechanisms of schisandrin B alleviates CCl4-induced liver fibrosis in rats by RNA-sequencing. schizandrin B C-C motif chemokine ligand 4 Rattus norvegicus
2 This study aimed to investigate the therapeutic effects and molecular mechanisms of Sch B against CCl4-induced liver fibrosis in rats. schizandrin B C-C motif chemokine ligand 4 Rattus norvegicus
3 The results demonstrated that Sch B effectively alleviated CCl4-induced liver damage and fibrosis in rats, as evidenced by improved liver function and decreased extracellular matrix deposition. schizandrin B C-C motif chemokine ligand 4 Rattus norvegicus
4 In conclusion, our study demonstrated Sch B alleviated CCl4-induced liver fibrosis by multiple modulatory mechanisms, which provide new clues for further pharmacological study of Sch B. schizandrin B C-C motif chemokine ligand 4 Rattus norvegicus