Title : Effect of danazol on gonadotropin and cAMP stimulated progesterone synthesis in cultured human granulosa cells.

Pub. Date : 1987 Aug

PMID : 3115021






2 Functional Relationships(s)
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1 In the presence of danazol (1 mg/l) the FSH-, LH- and hCG-stimulated progesterone synthesis was partially inhibited by 55 to 60%. Danazol hypertrichosis 2 (generalised, congenital) Homo sapiens
2 It was concluded that not only gonadotropin-stimulated steroid synthesis, as previously demonstrated for hCG, but also forskolin and 8-Bromo-cAMP-stimulated steroidogenesis is sensitive to danazol inhibition. Danazol hypertrichosis 2 (generalised, congenital) Homo sapiens