Title : Comparative efficacy and safety of dolutegravir relative to common core agents in treatment-naïve patients infected with HIV-1: a systematic review and network meta-analysis.

Pub. Date : 2019 May 30

PMID : 31146698






2 Functional Relationships(s)
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Protein Name
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1 CD4+ count increase was significantly greater with DTG than PIs (difference: 23.63-31.47 cells/muL) and efavirenz (difference: 34.54 cells/muL), and similar to other core agents. dolutegravir CD4 molecule Homo sapiens
2 DTG was more likely to result in patients achieving VS (probability: 94-100%), and a greater CD4+ count increase (probability: 53-100%) versus other core agents, including INSTIs (probability: 94-97% and 53-93%, respectively). dolutegravir CD4 molecule Homo sapiens