Pub. Date : 1986 Dec
PMID : 3114472
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In fibres depolarized by 50 mM-K, constant [K] X [Cl] in the presence of 1 mM-tetracaine (which blocks Ca release), the rate of pHi recovery from 5% CO2-induced acidification was 0.15 +/- 0.02 delta pHi h-1 (n = 7), whereas in depolarized fibres that had never been exposed to the drug, the rate of recovery was 0.27 +/- 0.01 delta pHi h-1 (n = 5). | Tetracaine | glucose-6-phosphate isomerase | Homo sapiens |
| 2 | In fibres depolarized by 50 mM-K, constant [K] X [Cl] in the presence of 1 mM-tetracaine (which blocks Ca release), the rate of pHi recovery from 5% CO2-induced acidification was 0.15 +/- 0.02 delta pHi h-1 (n = 7), whereas in depolarized fibres that had never been exposed to the drug, the rate of recovery was 0.27 +/- 0.01 delta pHi h-1 (n = 5). | Tetracaine | glucose-6-phosphate isomerase | Homo sapiens |
| 3 | In fibres depolarized by 50 mM-K, constant [K] X [Cl] in the presence of 1 mM-tetracaine (which blocks Ca release), the rate of pHi recovery from 5% CO2-induced acidification was 0.15 +/- 0.02 delta pHi h-1 (n = 7), whereas in depolarized fibres that had never been exposed to the drug, the rate of recovery was 0.27 +/- 0.01 delta pHi h-1 (n = 5). | Tetracaine | glucose-6-phosphate isomerase | Homo sapiens |
| 4 | Yet, when Ca release was not blocked and the depolarized fibres were exposed to tetracaine shortly before CO2 exposure, a similar slow rate of 0.14 +/- 0.03 delta pHi h-1 (n = 7) was observed. | Tetracaine | glucose-6-phosphate isomerase | Homo sapiens |
| 5 | Tetracaine reversibly inhibits pHi recovery, but this inhibition is not due to its blocking of Ca release. | Tetracaine | glucose-6-phosphate isomerase | Homo sapiens |