Pub. Date : 2019 May 7
PMID : 31139331
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Interestingly, we showed that EGFR is activated through an autocrine loop and that inhibition of the EGFR by the TKI, tyrphostin AG1478 or EGFR neutralizing antibodies strongly reduced activation of oncogenic ERK1/2 and mTOR/AKT downstream pathways. | Tyrphostins | epidermal growth factor receptor | Homo sapiens |
2 | Interestingly, we showed that EGFR is activated through an autocrine loop and that inhibition of the EGFR by the TKI, tyrphostin AG1478 or EGFR neutralizing antibodies strongly reduced activation of oncogenic ERK1/2 and mTOR/AKT downstream pathways. | Tyrphostins | epidermal growth factor receptor | Homo sapiens |
3 | Interestingly, we showed that EGFR is activated through an autocrine loop and that inhibition of the EGFR by the TKI, tyrphostin AG1478 or EGFR neutralizing antibodies strongly reduced activation of oncogenic ERK1/2 and mTOR/AKT downstream pathways. | Tyrphostins | epidermal growth factor receptor | Homo sapiens |