Pub. Date : 2019 May 28
PMID : 31126915
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tranexamic acid (TXA) is an antifibrinolytic agent that blocks plasmin formation. | Tranexamic Acid | plasminogen | Homo sapiens |
| 2 | Tranexamic acid (TXA) is an antifibrinolytic agent that blocks plasmin formation. | Tranexamic Acid | plasminogen | Homo sapiens |
| 3 | Because plasmin is known to promote inflammatory and immunosuppressive responses, we explored the possibility that plasmin-mediated immunosuppression in patients undergoing cardiac surgery can be directly reversed by TXA and decrease postoperative infection rates. | Tranexamic Acid | plasminogen | Homo sapiens |
| 4 | TXA was also shown to exert an immune-modulatory effect in healthy volunteers, further supporting the fibrin-independent effect of TXA on immune function and indicating that baseline plasmin levels contribute to the regulation of the immune system in the absence of any comorbidity or surgical trauma. | Tranexamic Acid | plasminogen | Homo sapiens |