Pub. Date : 2019 Jul 1
PMID : 31123185
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Serotonin (5-HT) is known to increase the rate of growth cone advance via cofilin-dependent increases in retrograde actin network flow and nonmuscle myosin II activity. | Serotonin | cofilin 1 | Homo sapiens |
| 2 | Serotonin (5-HT) is known to increase the rate of growth cone advance via cofilin-dependent increases in retrograde actin network flow and nonmuscle myosin II activity. | Serotonin | cofilin 1 | Homo sapiens |
| 3 | 5-HT simultaneously induces cofilin-dependent decreases in actin network density and PKC-dependent increases in point contact density. | Serotonin | cofilin 1 | Homo sapiens |
| 4 | Interestingly, when PKC activity was up-regulated, 5-HT treatments resulted in myosin II hyperactivation accompanied by catastrophic cofilin-dependent decreases in actin filament density, sudden decreases in traction force, and neurite retraction. | Serotonin | cofilin 1 | Homo sapiens |