Title : Studying the ShcD and ERK interaction under acute oxidative stress conditions in melanoma cells.

Pub. Date : 2019 Jul

PMID : 31121283






2 Functional Relationships(s)
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Protein Name
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1 Co-immunoprecipitation experiments revealed that ShcD mainly interacts with ERK in B16 and MM138 melanoma cells under both hydrogen peroxide-untreated and -treated conditions. Hydrogen Peroxide mitogen-activated protein kinase 1 Homo sapiens
2 The ShcD/ERK interaction promoted anti-survival signalling upon exposure to hydrogen peroxide, while U0126 treatment reduced death signalling. Hydrogen Peroxide mitogen-activated protein kinase 1 Homo sapiens