Title : [Effect of antioxidants on the activity of liver glutathione-S-, glucuronyl- and sulfurtransferases in rats].

Pub. Date : 1987 May-Jun

PMID : 3111882






2 Functional Relationships(s)
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1 It was shown that pretreatment of rats with antioxidants (AO) butylhydroxytoluene and 2-ethyl-6-methyl-3-hydroxypyridine hydrochloride owing to its effect of animal protection against intoxication with diethylnitrosamine (DENA) increases the liver activity of enzymes of stage II metabolism of xenobiotics: glutathione-S-transferase (GST), UDP-glucuronyltransferase (UDP-GT). 6-methyl-2-ethyl-3-hydroxypyridine UDP glucuronosyltransferase family 1 member A6 Rattus norvegicus
2 It was shown that pretreatment of rats with antioxidants (AO) butylhydroxytoluene and 2-ethyl-6-methyl-3-hydroxypyridine hydrochloride owing to its effect of animal protection against intoxication with diethylnitrosamine (DENA) increases the liver activity of enzymes of stage II metabolism of xenobiotics: glutathione-S-transferase (GST), UDP-glucuronyltransferase (UDP-GT). 6-methyl-2-ethyl-3-hydroxypyridine UDP glucuronosyltransferase family 1 member A6 Rattus norvegicus