Title : Associations of HLA genotypes with antithyroid drug-induced agranulocytosis: A systematic review and meta-analysis of pharmacogenomics studies.

Pub. Date : 2019 Sep

PMID : 31108563






2 Functional Relationships(s)
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Protein Name
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1 HLA-B*27:05, HLA-B*38:02, and HLA-DRB1*08:03 alleles were associated with ATD-induced agranulocytosis, especially in carbimazole/methimazole-induced agranulocytosis. Methimazole major histocompatibility complex, class II, DR beta 1 Homo sapiens
2 CONCLUSIONS: HLA-B*27:05, HLA-B*38:02 and HLA-DRB1*08:03 alleles were associated with ATD-induced agranulocytosis, especially in carbimazole/methimazole-induced agranulocytosis. Methimazole major histocompatibility complex, class II, DR beta 1 Homo sapiens