Pub. Date : 2019 Jul
PMID : 31108370
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | SIRT3 regulates cancer cell proliferation through deacetylation of PYCR1 in proline metabolism. | Proline | pyrroline-5-carboxylate reductase 1 | Homo sapiens |
| 2 | Pyrroline-5-carboxylate reductase 1 (PYCR1) participates in proline synthesis process by catalyzing the reduction of P5C to proline with concomitant generation of NAD+ and NADP+. | Proline | pyrroline-5-carboxylate reductase 1 | Homo sapiens |
| 3 | Pyrroline-5-carboxylate reductase 1 (PYCR1) participates in proline synthesis process by catalyzing the reduction of P5C to proline with concomitant generation of NAD+ and NADP+. | Proline | pyrroline-5-carboxylate reductase 1 | Homo sapiens |
| 4 | Pyrroline-5-carboxylate reductase 1 (PYCR1) participates in proline synthesis process by catalyzing the reduction of P5C to proline with concomitant generation of NAD+ and NADP+. | Proline | pyrroline-5-carboxylate reductase 1 | Homo sapiens |
| 5 | Pyrroline-5-carboxylate reductase 1 (PYCR1) participates in proline synthesis process by catalyzing the reduction of P5C to proline with concomitant generation of NAD+ and NADP+. | Proline | pyrroline-5-carboxylate reductase 1 | Homo sapiens |
| 6 | Our findings on the regulation of PYCR1 linked proline metabolism with SIRT3, CBP and cell growth, thus providing a potential approach for cancer therapy. | Proline | pyrroline-5-carboxylate reductase 1 | Homo sapiens |