Title : Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production.

Pub. Date : 2019 Apr 12

PMID : 31105869






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The family of isocitrate dehydrogenase (IDH) enzymes is vital for cellular metabolism, as IDH1 and IDH2 are required for the decarboxylation of isocitrate to alpha-ketoglutarate. isocitric acid isocitrate dehydrogenase (NADP(+)) 2 Homo sapiens